Ozone Therapy for Pain Management
In the contemporary era, characterized by demanding schedules, extended work hours, unhealthy dietary patterns, irregular sleep routines, limited opportunities for relaxation, substance misuse, and insufficient emotional support, various high-stress factors significantly impact our well-being. The repercussions manifest in the form of various ailments, with pain being the most prevalent.
An extensive survey revealed that 80% of individuals experiencing pain perceive it as an enduring medical condition, an inevitable facet of their daily existence. Addressing pain management conditions, medical Ozone Therapy emerges as a potential solution.
- Osteoarthritis (OA)
- Chronic Fatigue Syndrome
- Sacro-illiac joint Arthropathy
- Fibromyalgia
- Lumbago
- Rheumatoid Arthritis
Treatment Procedure
For the management of all pain conditions, targeted subcutaneous or articular ozone injections are employed to achieve localized analgesic effects. Additionally, systemic ozone therapy methods such as rectal insufflation, major autohemotherapy, or ozonized saline are utilized to enhance circulation and provide anti-inflammatory benefits.
Mechanism of Treatment
To address various pain conditions, a targeted approach involving subcutaneous or articular ozone injections is employed to yield localized analgesic outcomes. Additionally, systemic ozone therapy methods, such as rectal insufflation, major autohemotherapy, or ozonized saline, aim to enhance circulation and deliver anti-inflammatory effects.
The treatment’s mechanism of action involves several key elements:
- Inhibition of pro-inflammatory prostaglandin synthesis.
- Increased release of antagonists that counteract pro-inflammatory cytokines, including interleukin (IL)-1, IL-2, IL-8, IL-12, IL-15, interferon-Ω, and TNF-Ω.
- Elevated release of immunosuppressor cytokines, such as TGF B1 and IL-10.
- Release of bradykinin and algogenic compounds.
- Potential reactions between amino acids, precursors of CNS neuromodulators, and ozone.
- Ozone-induced acceleration of ATP synthesis through stimulation of aerobic glycolysis, enzyme activation, and its fundamental role in neuroplasticity (Moreleda, 1995).
- Anti-inflammatory effects attributed to the modulation of prostaglandins regulating cell reactions (Z. Fahmy, 1988).
- Increased oxygenation in tissues leading to accelerated metabolism and excretion of substances that activate nociceptive receptors.